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1

Yeast-derived recombinant human insulin-like growth factor I: Production, purification, and structural characterization

Steve Elliott, Katherine D. Fagin, Linda O. Narhi, James A. Miller, Matt Jones, Ray Koski, Mary Peters, Philip Hsieh, Raj Sachdev, Robert D. Rosenfeld, Michael F. Rohde, Tsutomu Arakawa

Journal:

The Protein Journal

Year:

1990

Language:

english

File:

PDF, 1.11 MB

english, 1990

2

Volatile Sulfur Production by Pig Cecal Bacteria in Batch Culture and Screening Inhibitors of Sulfate Reducing Bacteria.

ARAKAWA, Tsutomu, ISHIKAWA, Yoshimi, USHIDA, Kazunari

Journal:

Journal of Nutritional Science and Vitaminology

Year:

2000

Language:

english

File:

PDF, 1.18 MB

english, 2000

3

Volatile Sulfur Production in the Large Intestine as Affected by Plant Extracts in Pig In Vitro Model

ISHIKAWA, Yoshimi, MAEKAWA, Makiko, ARAKAWA, Tsutomu, USHIDA, Kazunari

Journal:

Bioscience and Microflora

Year:

2001

Language:

english

File:

PDF, 714 KB

english, 2001

4

Influence of Dietary Supplementation of Herb Extracts on Volatile Sulfur Production in Pig Large Intestine.

USHIDA, Kazunari, MAEKAWA, Makiko, ARAKAWA, Tsutomu

Journal:

Journal of Nutritional Science and Vitaminology

Year:

2002

Language:

english

File:

PDF, 1.26 MB

english, 2002

5

Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase

Kunio S. Misono, John S. Philo, Tsutomu Arakawa, Craig M. Ogata, Yue Qiu, Haruo Ogawa, Howard S. Young

Journal:

Year:

2011

Language:

english

File:

PDF, 601 KB

english, 2011

6

Developments and Challenges for mAb-Based Therapeutics

Goswami, Sumit, Wang, Wei, Arakawa, Tsutomu, Ohtake, Satoshi

Journal:

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

7

[Methods in Enzymology] Diffraction Methods for Biological Macromolecules Part A Volume 114 || [3]Theory of protein solubility

Arakawa, Tsutomu

Year:

1985

Language:

english

File:

PDF, 1.25 MB

english, 1985

8

Induction of α-Helix in the β-Sheet Protein Tumor Necrosis Factor-α: Thermal- and Trifluoroethanol-Induced Denaturation at Neutral pH

Narhi, Linda Owers, Philo, John S., Li, Tiansheng, Zhang, Mei, Samal, Babru, Arakawa, Tsutomu

Journal:

Year:

1996

Language:

english

File:

PDF, 356 KB

english, 1996

9

Antiviral and Virucidal Activities of Natural Products

Arakawa, Tsutomu, Yamasaki, Hisashi, Ikeda, Keiko, Ejima, Daisuke, Naito, Takeshi, Koyama, A.

Journal:

Current Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 648 KB

english, 2009

10

Insoluble expression of highly soluble halophilic metal binding protein for metal ion biosorption: Application of aggregation-prone peptide from hen egg white lysozyme

Tokunaga, Masao, Arakawa, Tsutomu, Tokunaga, Yuhei, Sugimoto, Yasushi, Ishibashi, Matsujiro

Journal:

Protein Expression and Purification

Year:

2019

Language:

english

File:

PDF, 1.59 MB

english, 2019

11

Mechanism of polyethylene glycol interaction with proteins

Arakawa, Tsutomu, Timasheff, Serge N.

Journal:

Year:

1985

Language:

english

File:

PDF, 864 KB

english, 1985

12

The effects of allantoin, arginine and NaCl on thermal melting and aggregation of ribonuclease, bovine serum albumin and lysozyme

Arakawa, Tsutomu, Maluf, Nasib Karl

Journal:

International Journal of Biological Macromolecules

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

13

Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial

Tohru Kobayashi, Tsutomu Saji, Tetsuya Otani, Kazuo Takeuchi, Tetsuya Nakamura, Hirokazu Arakawa, Taichi Kato, Toshiro Hara, Kenji Hamaoka, Shunichi Ogawa, Masaru Miura, Yuichi Nomura, Shigeto Fuse, F

Journal:

Year:

2012

Language:

english

File:

PDF, 209 KB

english, 2012

14

Protection of bovine serum albumin from aggregation by Tween 80

Tsutomu Arakawa, Yoshiko Kita

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 432 KB

english, 2000

15

Study on left atrial contractile performance. Participation of Frank-Starling mechanism.

YAMAGUCHI, MASATO, ARAKAWA, MICHIO, TANAKA, TSUTOMU, TAKAYA, TADATAKE, NAGANO, TOSHIHIKO, HIRAKAWA, SENRI

Journal:

Japanese Circulation Journal

Year:

1987

File:

PDF, 852 KB

1987

16

The effects of arginine on protein binding and elution in hydrophobic interaction and ion-exchange chromatography

Tsutomu Arakawa, Kouhei Tsumoto, Kazuo Nagase, Daisuke Ejima

Journal:

Protein Expression and Purification

Year:

2007

Language:

english

File:

PDF, 176 KB

english, 2007

17

Highly efficient production of VHH antibody fragments in Brevibacillus choshinensis expression system

Mizukami, Makoto, Tokunaga, Hiroko, Onishi, Hiromasa, Ueno, Yohei, Hanagata, Hiroshi, Miyazaki, Nobuo, Kiyose, Norihiko, Ito, Yuji, Ishibashi, Matsujiro, Hagihara, Yoshihisa, Arakawa, Tsutomu, Miyauch

Journal:

Protein Expression and Purification

Year:

2015

Language:

english

File:

PDF, 2.43 MB

english, 2015

18

Aggregation behaviors of glutens, glutenins and gliadins from various wheats.

ARAKAWA, Tsutomu, MORISHITA, Hideaki, YONEZAWA, Daizo

Journal:

Agricultural and Biological Chemistry

Year:

1976

Language:

english

File:

PDF, 1.22 MB

english, 1976

19

Effects of correcting missing daily feed intake values on the genetic parameters and estimated breeding values for feeding traits in pigs

Ito, Tetsuya, Fukawa, Kazuo, Kamikawa, Mai, Nikaidou, Satoshi, Taniguchi, Masaaki, Arakawa, Aisaku, Tanaka, Genki, Mikawa, Satoshi, Furukawa, Tsutomu, Hirose, Kensuke

Journal:

Animal Science Journal

Year:

2017

Language:

english

File:

PDF, 209 KB

english, 2017

20

Arginine as a Synergistic Virucidal Agent

Ohtake, Satoshi, Arakawa, Tsutomu, Koyama, A. Hajime

Journal:

Year:

2010

Language:

english

File:

PDF, 512 KB

english, 2010

21

Solubilization of active green fluorescent protein from insoluble particles by guanidine and arginine

Kouhei Tsumoto, Mitsuo Umetsu, Izumi Kumagai, Daisuke Ejima, Tsutomu Arakawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 134 KB

english, 2003

22

Nondenaturing solubilization of β2 microglobulin from inclusion bodies by l-arginine

Mitsuo Umetsu, Kouhei Tsumoto, Shigeki Nitta, Tadafumi Adschiri, Daisuke Ejima, Tsutomu Arakawa, Izumi Kumagai

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 491 KB

english, 2005

23

Corrigendum to “Mechanism of protein desorption from 4-mercaptoethylpyridine resins by arginine solutions” [J. Chromatogr. A 1373 (2014) 141–148]

Hirano, Atsushi, Maruyama, Takuya, Shiraki, Kentaro, Arakawa, Tsutomu, Kameda, Tomoshi

Journal:

Journal of Chromatography A

Year:

2018

Language:

english

File:

PDF, 615 KB

english, 2018

24

Effects of allantoin and dimethyl sulfoxide on the thermal aggregation of lysozyme

Nishinami, Suguru, Hirano, Atsushi, Arakawa, Tsutomu, Shiraki, Kentaro

Journal:

International Journal of Biological Macromolecules

Year:

2018

Language:

english

File:

PDF, 934 KB

english, 2018

25

Practical considerations in refolding proteins from inclusion bodies

Kouhei Tsumoto, Daisuke Ejima, Izumi Kumagai, Tsutomu Arakawa

Journal:

Protein Expression and Purification

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

26

Mechanism of protein precipitation and stabilization by co-solvents

Serge N. Timasheff, Tsutomu Arakawa

Journal:

Journal of Crystal Growth

Year:

1988

Language:

english

File:

PDF, 540 KB

english, 1988

27

Contribution of the Surface Free Energy Perturbation to Protein-Solvent Interactions

Kita, Yoshiko, Arakawa, Tsutomu, Lin, Tiao-Yin, Timasheff, Serge N.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.31 MB

english, 1994

28

Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

Iwahara, Toshinori, Fujimoto, Jiro, Wen, Duanzhi, Cupples, Rod, Bucay, Nathan, Arakawa, Tsutomu, Mori, Shigeo, Ratzkin, Barry, Yamamoto, Tadashi

Journal:

Year:

1997

Language:

english

File:

PDF, 901 KB

english, 1997

29

Suppression of protein interactions by arginine: A proposed mechanism of the arginine effects

Tsutomu Arakawa, Daisuke Ejima, Kouhei Tsumoto, Noriyuki Obeyama, Yoshikazu Tanaka, Yoshiko Kita, Serge N. Timasheff

Journal:

Biophysical Chemistry

Year:

2007

Language:

english

File:

PDF, 391 KB

english, 2007

30

ChemInform Abstract: Applications of Analytical Ultracentrifuge to Molecular Biology and Pharmaceutical Science

Tsutomu Arakawa, John S. Philo

Journal:

Year:

1999

File:

PDF, 25 KB

1999

31

Binding and Elution Properties of Mixed-Mode Chromatography and Its Applications for Purification

Arakawa, Tsutomu, Santarelli, Xavier

Journal:

Current Protein & Peptide Science

Year:

2018

Language:

english

File:

PDF, 107 KB

english, 2018

32

Applications of Analytical Ultracentrifuge to Molecular Biology and Pharmaceutical Science

ARAKAWA, Tsutomu, PHILO, John S.

Journal:

YAKUGAKU ZASSHI

Year:

1999

File:

PDF, 1.03 MB

1999

33

Screening of effective column rinse solvent for Protein-A chromatography

Ryosuke Yumioka, Kouhei Tsumoto, Tsutomu Arakawa, Daisuke Ejima

Journal:

Protein Expression and Purification

Year:

2010

Language:

english

File:

PDF, 370 KB

english, 2010

34

ChemInform Abstract: Role of Arginine in Development of Biopharmaceuticals

Tsutomu Arakawa

Journal:

Year:

2010

File:

PDF, 14 KB

2010

35

Strategies to suppress aggregation of recombinant keratinocyte growth factor during liquid formulation development

Bao-Lu Chen, Tsutomu Arakawa, Eric Hsu, Linda O. Narhi, Timothy J. Tressel, Shu Lin Chien

Journal:

Journal of Pharmaceutical Sciences

Year:

1994

Language:

english

File:

PDF, 713 KB

english, 1994

36

Refractive Index of Proteins in Aqueous Sodium Chloride

Jie Wen, Tsutomu Arakawa

Journal:

Analytical Biochemistry

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

37

Arginine improves protein elution in hydrophobic interaction chromatography: The cases of human interleukin-6 and activin-A

Kouhei Tsumoto, Daisuke Ejima, Kazuo Nagase, Tsutomu Arakawa

Journal:

Journal of Chromatography A

Year:

2007

Language:

english

File:

PDF, 198 KB

english, 2007

38

Detection of cytochrome C by means of surface plasmon resonance sensor

Tsutomu Ishihara, Tsuyoshi Arakawa

Journal:

Sensors and Actuators B: Chemical

Year:

2003

Language:

english

File:

PDF, 107 KB

english, 2003

39

The importance of Arg40 and 45 in the mitogenic activity and structural stability of basic fibroblast growth factor: Effects of acidic amino acid substitutions

Tsutomu Arakawa, Paige Hoist, Linda O. Narhi, John S. Philo, Jie Wen, Steven J. Prestrelski, Xiaotian Zhu, Douglas C. Rees, Gary M. Fox

Journal:

The Protein Journal

Year:

1995

Language:

english

File:

PDF, 923 KB

english, 1995

40

Diastolic compliance of the left atrium in man: A determinant of preload of the left ventricle

Toshihiko Nagano, Michio Arakawa, Tsutomu Tanaka, Masato Yamaguchi, Tadatake Takaya, Toshiyuki Noda, Hiroshi Miwa, Kensaku Kagawa, Senri Hirakawa

Journal:

Heart and Vessels

Year:

1989

Language:

english

File:

PDF, 848 KB

english, 1989

41

Stabilization of protein structure by sugars

Arakawa, Tsutomu, Timasheff, Serge N.

Journal:

Year:

1982

Language:

english

File:

PDF, 1.01 MB

english, 1982

42

Preferential interactions determine protein solubility in three-component solutions: the magnesium chloride system

Arakawa, Tsutomu, Bhat, Rajiv, Timasheff, Serge N.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.19 MB

english, 1990

43

Expression, Purification, and Characterization of the Active Immunoglobulin-like Domain of Human Granulocyte-Colony-Stimulating Factor Receptor in Escherichia coli

Matsujiro Ishibashi, Hiroko Tokunaga, Tsutomu Arakawa, Masao Tokunaga

Journal:

Protein Expression and Purification

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

44

The mechanism of helical transition of proteins by organic solvents

Tsutomu Arakawa, Dean Goddette

Journal:

Archives of Biochemistry and Biophysics

Year:

1985

Language:

english

File:

PDF, 838 KB

english, 1985

45

The solubility of nucleobases in aqueous arginine solutions

Atsushi Hirano, Hiroko Tokunaga, Masao Tokunaga, Tsutomu Arakawa, Kentaro Shiraki

Journal:

Archives of Biochemistry and Biophysics

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

46

Is arginine a protein-denaturant?

Matsujiro Ishibashi, Kouhei Tsumoto, Masao Tokunaga, Daisuke Ejima, Yoshiko Kita, Tsutomu Arakawa

Journal:

Protein Expression and Purification

Year:

2005

Language:

english

File:

PDF, 159 KB

english, 2005

47

Dimerization of the Extracellular Domain of Granulocyte-Colony Stimulating Factor Receptor by Ligand Binding: A Monovalent Ligand Induces 2:2 Complexes

Horan, Tom, Wen, Jie, Narhi, Linda, Parker, Vann, Garcia, Andy, Arakawa, Tsutomu, Philo, John

Journal:

Year:

1996

Language:

english

File:

PDF, 565 KB

english, 1996

48

Role of native disulfide bonds in the structure and activity of insulin-like growth factor 1: Genetic models of protein-folding intermediates

Narhi, Linda Owers, Hua, Qing Xin, Arakawa, Tsutomu, Fox, G. Michael, Tsai, Larry, Rosenfeld, Robert, Holst, Paige, Miller, James A., Weiss, Michael A.

Journal:

Year:

1993

Language:

english

File:

PDF, 908 KB

english, 1993

49

Charge state of arginine as an additive on heat-induced protein aggregation.

Miyatake, Takumi, Yoshizawa, Shunsuke, Arakawa, Tsutomu, Shiraki, Kentaro

Journal:

International Journal of Biological Macromolecules

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

50

Optical Control of Transmittance by Photo-Induced Absorption Effect in InGaN/GaN Structures

Nomura, Masahiro, Arakawa, Yasuhiko, Shimura, Tsutomu, Kuroda, Kazuo

Journal:

Japanese Journal of Applied Physics

Year:

2005

Language:

english

File:

PDF, 305 KB

english, 2005

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